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Durlobactam/Sulbactam Injection (SULBACTAM/DURLOBACTAM - INJECTION)

For pneumonia.

Brand Name(s): Xacduro

Generic Name: Durlobactam/Sulbactam

Instructions

This medicine is given as an IV injection into a vein.

This medicine is given gradually through the IV line.

This medicine should be given over 3 hours.

Carefully follow the instructions for preparing this medicine before injection.

Read and make sure you understand the instructions for measuring dose and using syringe. If you have any questions, talk to your doctor, nurse, or pharmacist.

The medicine needs to be mixed before being injected.

Follow package direction for diluting medicine with IV fluids or as instructed by your doctor or nurse.

Always inspect the medicine before using.

The liquid should be yellow to orange in color.

Do not use the medicine if it contains any particles or if it has changed color.

Gently turn the medicine upside down several times to mix the medicine before using.

Keep this medicine in the refrigerator. Do not freeze.

Take the medicine out of the refrigerator about 15 to 30 minutes before use to warm to room temperature.

Never use any medicine that has expired.

Discard any unused, mixed medicine after 24 hours in refrigerator.

Wash your hands before and after handling this medicine.

Use this medicine at the same time each day.

Space doses evenly to keep a steady amount of medicine in the body.

Ask your doctor, nurse or pharmacist to show you how to use this medicine correctly.

If you miss a dose, contact your doctor for instructions.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Tell your doctor if symptoms do not get better or if they get worse.

Keep using this medicine for the full number of days that it is prescribed. Do not stop the medicine even if you start to feel better.

Keep all appointments for medical exams and tests while on this medicine.

Cautions

During pregnancy, this medicine should be used only when clearly needed. Talk to your doctor about the risks and benefits.

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

Do not use the medication any more than instructed.

Contact your doctor if you develop any signs of a new infection such as fever, cough, sore throat, or chills.

Speak with your health care provider before receiving any vaccinations.

Please tell your doctor if you have moderate to severe diarrhea while on this medicine. Do not treat the diarrhea with over-the-counter diarrhea medicine.

This medicine passes into breast milk. Ask your doctor before breastfeeding.

Ask your pharmacist how to properly throw away used needles or syringes.

Do not share this medicine with anyone who has not been prescribed this medicine.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

  • diarrhea

Call your doctor or get medical help right away if you notice any of these more serious side effects:

  • severe or persistent abdominal pain
  • rapid breathing
  • severe, watery or bloody diarrhea
  • fast or irregular heart beats
  • signs of liver damage (such as yellowing of eye or skin, dark urine, or unusual tiredness)
  • muscle cramps
  • pale or blue skin, lips or fingernails
  • seizures
  • yeast infection of mouth
  • vaginal itching or yeast infection

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.

Please speak with your doctor, nurse, or pharmacist if you have any questions about this medicine.